Acetyl tetrapeptide-5
is used in cosmetic eye formulations to decrease puffiness, eye bags, and dark circles by reducing edema and protecting proteins such as SOD from glycation
Alanine
Ala / A · hydrophobic residue · neutral charge
AOD-9604
is studied as an anti-obesity peptide that can reduce weight gain and increase fat oxidation in obese animal models with generally neutral effects on IGF-1 and glucose metabolism in early human trials
Arginine
Arg / R · basic residue · positive charge
Argireline
is a topical cosmetic peptide reported to decrease dynamic wrinkles by partially mimicking the mechanism of botulinum toxin in a non-invasive manner
Asparagine
Asn / N · polar residue · neutral charge
Aspartic acid
Asp / D · acidic residue · negative charge
BPC-157
is investigated for accelerating healing of gastrointestinal mucosa, tendons, ligaments, bone, and nervous tissue in preclinical models, with anti-inflammatory and pro-angiogenic effects
Comparison
While MGF is upregulated in muscle after mechanical overload, where it supports tissue repair and growth; recombinant forms are studied for regenerative and performance-enhancement effects22138, Selank is a peptide developed in Russia as an anxiolytic and nootropic; in animal models it reduces anxiety-like behavior and modulates immune parameters under stress39.
While MGF works as a 24-amino-acid E-peptide splice variant of IGF-1 (IGF-1Ec) produced in mechanically stressed or damaged muscle that activates IGF1R and local anabolic pathways involved in muscle repair and hypertrophy22138144, Selank is a synthetic heptapeptide, Thr-Lys-Pro-Arg-Pro-Gly-Pro, that combines a tuftsin fragment with a Pro-Gly-Pro motif and is reported to modulate GABAergic neurotransmission and cytokine balance while being resistant to proteolytic degradation39.
MGF
IGF1
Selank
Not assigned in the current dataset.
The clearest overlap between MGF and Selank is that both converge around Signaling modulator. Their typical research and application settings separate fairly clearly: MGF is more often discussed in the realm of Musculoskeletal health, whereas Selank is more often associated with the realm of Neurology and brain health and Immunology and inflammation. Both appear to work through Signaling modulator, but the functional emphasis still separates, with MGF leaning toward Anabolic growth and Tissue repair and healing and Selank leaning toward Anxiolytic and sleep modulation and Immune regulation. MGF has a more natural endogenous origin, while Selank is closer to synthetic analog background with MGF in Preclinical development and Selank approved for Research use only. Their sequence patterns also diverge, with MGF showing protein-mimetic sequence features and Selank showing proline-rich features.
No related articles are linked to these peptides yet.