Peptable

Acetyl tetrapeptide-5

is used in cosmetic eye formulations to decrease puffiness, eye bags, and dark circles by reducing edema and protecting proteins such as SOD from glycation

Peptide

Alanine

Ala / A · hydrophobic residue · neutral charge

Amino acid

AOD-9604

is studied as an anti-obesity peptide that can reduce weight gain and increase fat oxidation in obese animal models with generally neutral effects on IGF-1 and glucose metabolism in early human trials

Peptide

Arginine

Arg / R · basic residue · positive charge

Amino acid

Argireline

is a topical cosmetic peptide reported to decrease dynamic wrinkles by partially mimicking the mechanism of botulinum toxin in a non-invasive manner

Peptide

Asparagine

Asn / N · polar residue · neutral charge

Amino acid

Aspartic acid

Asp / D · acidic residue · negative charge

Amino acid

BPC-157

is investigated for accelerating healing of gastrointestinal mucosa, tendons, ligaments, bone, and nervous tissue in preclinical models, with anti-inflammatory and pro-angiogenic effects

Peptide

Peptide record

Acetyl tetrapeptide-5

Function

Acetyl tetrapeptide-5 is a Signal peptide.

This Peptide is used in cosmetic eye formulations to decrease puffiness, eye bags, and dark circles by reducing edema and protecting proteins such as SOD from glycation51150159154

Mechanism

Acetyl tetrapeptide-5 is a synthetic tetrapeptide, Ac-βAla-His-Ser-His (Eyeseryl), with reported ACE-1 inhibition and anti-glycation activity, proposed to improve microcirculation and reduce capillary permeability and fluid accumulation in periorbital tissues51150159157

Acetyl tetrapeptide-5 is a Signaling modulator.

Receptor

Acts as an enzyme inhibitor (eg, ACE-1, glycation-related pathways) rather than via a specific membrane receptor51159

Length

4 amino acids

Organism or Origin

Fully synthetic cosmetic peptide (Eyeseryl) 150157

Gene

Not assigned in the current dataset.

Sequence

AcN-terminus
βAla
His
Ser
His
C-terminusOH

Ac-βAla-H-S-H-OH 150153157

βAla, Histidine, Serine, Histidine

4 residuesapprox. 361.36 Dacharge +2 / -0 / net +2basic 2 • polar 11 residues without standard metadata

Sequence-derived properties

Sequence-derived properties are omitted because the stored sequence includes non-residue terminal modifiers.

Sequence-derived properties are omitted because one or more residues are not present in the standard amino-acid dataset.

Sources

  1. 51[PDF] Acetyl tetrapeptide-5 - SkinMiles, https://skinmiles.com/wp-content/uploads/2017/12/Matriskin-Ingredients.pdf
  2. 150The important eye peptide of acetyl tetrapeptide-5 - ChemicalBook, https://www.chemicalbook.com/article/the-important-eye-peptide-of-acetyl-tetrapeptide-5.htm
  3. 153Acetyl Tetrapeptide-5 (Eyeseryl) | CAS 820959-17-9 Manufacturer ..., https://www.conscientia-industrial.com/peptides/acetyl-tetrapeptide-5-eyeseryl-cas-820959-17-9
  4. 154Bioactive peptides in cosmetic formulations: Review of ..., https://www.sciencedirect.com/science/article/pii/S0196978125001019
  5. 157Effects of Peptides in Cosmetics, https://aapep.bocsci.com/resources/cosmetic-peptides.html
  6. 159Acetyl tetrapeptide-5 | ACE-1 Inhibitor | MedChemExpress, https://www.medchemexpress.com/acetyl-tetrapeptide-5.html

Related articles

No related articles are linked to this peptide yet.