Peptable

Peptide record

Argireline

Function

Argireline is a Neuropeptide.

This Peptide is a topical cosmetic peptide reported to decrease dynamic wrinkles by partially mimicking the mechanism of botulinum toxin in a non-invasive manner49

Mechanism

Argireline is acetyl hexapeptide-8 (Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2), a SNAP-25–mimetic peptide that competitively inhibits SNARE complex assembly, reducing acetylcholine release at neuromuscular junctions and attenuating facial muscle contraction4959

Argireline is a Neurotransmitter modulator.

Receptor

Molecular target is the SNARE complex component SNAP-25 rather than a classical receptor; it interferes with SNAP-25 participation in vesicle fusion49

Length

6 amino acids

Organism or Origin

Fully synthetic neuropeptide used in cosmetic formulations49

Gene

Not assigned in the current dataset.

Sequence

AcN-terminusC-terminusNH2

Ac-EEMQRR-NH2 4959

Glutamic acid, Glutamic acid, Methionine, Glutamine, Arginine, Arginine

6 residuesapprox. 829.94 Dacharge +2 / -2 / net +0acidic 2 • hydrophobic 1 • polar 1 • basic 2

Sequence-derived properties

Sequence-derived properties are omitted because the stored sequence includes non-residue terminal modifiers.

Sources

  1. 49Acetyl Hexapeptide-8 - Argireline - ChemPep, https://chempep.com/product/acetyl-hexapeptide-8/
  2. 59Argireline (Acetyl Hexapeptide-8), https://grindergym.com/argireline-acetyl-hexapeptide-8/

Related articles

No related articles are linked to this peptide yet.