Peptable

Peptide record

Argireline

Function

Argireline is a Neuropeptide.

This Peptide is a topical cosmetic peptide reported to decrease dynamic wrinkles by partially mimicking the mechanism of botulinum toxin in a non-invasive manner49

Mechanism

Argireline is acetyl hexapeptide-8 (Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2), a SNAP-25–mimetic peptide that competitively inhibits SNARE complex assembly, reducing acetylcholine release at neuromuscular junctions and attenuating facial muscle contraction4959

Argireline is a Neurotransmitter modulator.

Receptor

Molecular target is the SNARE complex component SNAP-25 rather than a classical receptor; it interferes with SNAP-25 participation in vesicle fusion49

Length

6 amino acids

Organism or Origin

Fully synthetic neuropeptide used in cosmetic formulations49

Gene

Not assigned in the current dataset.

Sequence

AcN-terminusC-terminusNH2

Ac-EEMQRR-NH2 4959

Glutamic acid, Glutamic acid, Methionine, Glutamine, Arginine, Arginine

6 residuesapprox. 829.94 Dacharge +2 / -2 / net +0acidic 2 • hydrophobic 1 • polar 1 • basic 2

Sequence-derived properties

Sequence-derived properties are omitted because the stored sequence includes non-residue terminal modifiers.

Sources

  1. 49Acetyl Hexapeptide-8 - Argireline - ChemPep, https://chempep.com/product/acetyl-hexapeptide-8/
  2. 59Argireline (Acetyl Hexapeptide-8), https://grindergym.com/argireline-acetyl-hexapeptide-8/

Related articles

No related articles are linked to this peptide yet.

About this page

Published by
Peptable, as a structured reference dataset.
Dataset updated
Sourcing
Compiled from published literature and reference databases. See the editorial policy.

This page is reference information, not medical advice, and describes no dosages or administration protocols. Read the full disclaimer.