Peptide record

Argireline

Mechanism

Acetyl hexapeptide-8 (Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2), a SNAP-25–mimetic peptide that competitively inhibits SNARE complex assembly, reducing acetylcholine release at neuromuscular junctions and attenuating facial muscle contraction.49 59

Function

Topical cosmetic peptide reported to decrease dynamic wrinkles by partially mimicking the mechanism of botulinum toxin in a non-invasive manner.49

Receptor

Molecular target is the SNARE complex component SNAP-25 rather than a classical receptor; it interferes with SNAP-25 participation in vesicle fusion.49

Sequence

Ac-Glu-Glu-Met-Gln-Arg-Arg-NH249 59

Length

6 amino acids

Organism or Origin

Fully synthetic neuropeptide used in cosmetic formulations.49

Gene

Not assigned in the current dataset.

Sources

49Acetyl Hexapeptide-8 - Argireline - ChemPep, https://chempep.com/product/acetyl-hexapeptide-8/
59Argireline (Acetyl Hexapeptide-8), https://grindergym.com/argireline-acetyl-hexapeptide-8/

No related articles are linked to this peptide yet.