Peptable

Peptide record

Selank

Function

Selank is a Neuropeptide.

This Peptide is a peptide developed in Russia as an anxiolytic and nootropic; in animal models it reduces anxiety-like behavior and modulates immune parameters under stress39

Mechanism

Selank is a synthetic heptapeptide, Thr-Lys-Pro-Arg-Pro-Gly-Pro, that combines a tuftsin fragment with a Pro-Gly-Pro motif and is reported to modulate GABAergic neurotransmission and cytokine balance while being resistant to proteolytic degradation39

Selank is a Neurotransmitter modulator.

Receptor

Not clearly established in the current dataset.

Length

7 amino acids

Organism or Origin

Synthetic analog of the IgG-derived tetrapeptide tuftsin39

Gene

Not assigned in the current dataset.

Sequence

N-terminusC-terminus

TKPRPGP 39

Threonine, Lysine, Proline, Arginine, Proline, Glycine, Proline

7 residuesapprox. 733.88 Dacharge +2 / -0 / net +2polar 1 • basic 2 • special 4

Sequence-derived properties

Length

7 residues

Molecular weight

751.9 Da

Average hydrophobicity

-2.04

Unique amino acids

5

Residue class composition

special

4 (57.1%)

basic

2 (28.6%)

polar

1 (14.3%)

Charge-category composition

neutral

5 (71.4%)

positive

2 (28.6%)

Amino acid composition

Proline (Pro/P)

3 (42.9%)

Arginine (Arg/R)

1 (14.3%)

Glycine (Gly/G)

1 (14.3%)

Lysine (Lys/K)

1 (14.3%)

Threonine (Thr/T)

1 (14.3%)

Sources

  1. 39Application of thr-lys-pro-arg-pro-gly-pro peptide (selank) for ..., https://patents.google.com/patent/RU2629832C1/en

Related articles

No related articles are linked to this peptide yet.

About this page

Published by
Peptable, as a structured reference dataset.
Dataset updated
Sourcing
Compiled from published literature and reference databases. See the editorial policy.

This page is reference information, not medical advice, and describes no dosages or administration protocols. Read the full disclaimer.