Function
Selank is a Neuropeptide.
This Peptide is a peptide developed in Russia as an anxiolytic and nootropic; in animal models it reduces anxiety-like behavior and modulates immune parameters under stress39
Peptide record
Selank
Peptide record
Selank
Mechanism
Selank is a synthetic heptapeptide, Thr-Lys-Pro-Arg-Pro-Gly-Pro, that combines a tuftsin fragment with a Pro-Gly-Pro motif and is reported to modulate GABAergic neurotransmission and cytokine balance while being resistant to proteolytic degradation39
Selank is a Neurotransmitter modulator.
Receptor
Not clearly established in the current dataset.
Length
7 amino acids
Organism or Origin
Synthetic analog of the IgG-derived tetrapeptide tuftsin39
Gene
Not assigned in the current dataset.
Sequence
TKPRPGP 39
Threonine, Lysine, Proline, Arginine, Proline, Glycine, Proline
7 residuesapprox. 733.88 Dacharge +2 / -0 / net +2polar 1 • basic 2 • special 4
Sequence-derived properties
Length
7 residues
Molecular weight
751.9 Da
Average hydrophobicity
-2.04
Unique amino acids
5
Residue class composition
special
4 (57.1%)
basic
2 (28.6%)
polar
1 (14.3%)
Charge-category composition
neutral
5 (71.4%)
positive
2 (28.6%)
Amino acid composition
Proline (Pro/P)
3 (42.9%)
Arginine (Arg/R)
1 (14.3%)
Glycine (Gly/G)
1 (14.3%)
Lysine (Lys/K)
1 (14.3%)
Threonine (Thr/T)
1 (14.3%)
Sources
- 39Application of thr-lys-pro-arg-pro-gly-pro peptide (selank) for ..., https://patents.google.com/patent/RU2629832C1/en
Related articles
No related articles are linked to this peptide yet.