Function

SS-31 is a Mitochondrial peptide.

This Peptide improves mitochondrial bioenergetics, reduces oxidative stress, and shows protective effects in models of ischemia-reperfusion, neurodegeneration, and other mitochondrial disorders4637137

Mechanism

SS-31 is a mitochondria-targeted tetrapeptide, d-Arg-dimethylTyr-Lys-Phe-NH2, that selectively binds cardiolipin in the inner mitochondrial membrane, stabilizing cristae structure, improving electron transport, and reducing ROS production4637137143

SS-31 is a Signaling modulator.

Receptor

Cardiolipin-rich inner mitochondrial membrane; interacts with cardiolipin and associated mitochondrial proteins rather than a classical cell-surface receptor46137143

Length

4 amino acids

Organism or Origin

Fully synthetic Szeto–Schiller tetrapeptide; not encoded in the genome4637

Gene

Not assigned in the current dataset.