Peptide record

Epitalon

Mechanism

Synthetic tetrapeptide Ala-Glu-Asp-Gly (AEDG) that has been shown to bind histones and modulate gene expression and chromatin state, with reported effects on pineal function, neurogenesis, and longevity in animal models.36

Function

Reported to increase lifespan and reduce tumor incidence in animals, and to influence differentiation of neural and mesenchymal stem cells; studied as an epigenetic regulatory peptide.36

Receptor

Binds nuclear histone proteins (H1, H2B, H3, H4) rather than a classic membrane receptor.36

Sequence

Ala-Glu-Asp-Gly (AEDG)36

Length

4 amino acids

Organism or Origin

Synthetic peptide modeled after a pineal gland peptide fraction; not directly encoded as a standalone peptide in humans.36

Gene

Not assigned in the current dataset.

Sources

36AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein ..., https://pmc.ncbi.nlm.nih.gov/articles/PMC7037223/

No related articles are linked to this peptide yet.