Comparison
While KPV is investigated as an anti-inflammatory and barrier-protective agent in skin and mucosal models, reducing pro-inflammatory cytokines and promoting tissue repair684, Matrixyl is a widely used cosmetic peptide with evidence of stimulating extracellular matrix synthesis and reducing wrinkle appearance in skin-care formulations48.
While KPV works as the C-terminal Lys-Pro-Val tripeptide fragment of α-MSH, which exerts potent anti-inflammatory effects largely via inhibition of NF-κB signaling and modulation of cytokine expression, with many actions independent of classical melanocortin receptor activation684, Matrixyl is a palmitoylated pentapeptide, Pal-Lys-Thr-Thr-Lys-Ser (Pal-KTTKS), that acts as a matrikine, signaling to dermal fibroblasts to increase production of collagen, elastin, fibronectin, and other ECM components4858.
KPV is 3 amino acids long, whereas Matrixyl is longer as it has a length of 5 amino acids. KPV is made up of a sequence of Lysine, Proline, Valine. Matrixyl is made up of a sequence of Lysine, Threonine, Threonine, Lysine, Serine.
KPV
POMC
Matrixyl
Not assigned in the current dataset.
No related articles are linked to these peptides yet.