Peptable

Peptide record

Matrixyl

Function

Matrixyl is a Matrikine.

This Peptide is a widely used cosmetic peptide with evidence of stimulating extracellular matrix synthesis and reducing wrinkle appearance in skin-care formulations48

Mechanism

Matrixyl is a palmitoylated pentapeptide, Pal-Lys-Thr-Thr-Lys-Ser (Pal-KTTKS), that acts as a matrikine, signaling to dermal fibroblasts to increase production of collagen, elastin, fibronectin, and other ECM components4858

Matrixyl is a Matrix remodeling modulator.

Receptor

Not clearly established in the current dataset.

Length

5 amino acids

Organism or Origin

Synthetic lipopeptide derived from a collagen I C-terminal fragment sequence5158

Gene

Not assigned in the current dataset.

Sequence

PalmitoylN-terminusC-terminus

Palmitoyl-KTTKS 4858

Lysine, Threonine, Threonine, Lysine, Serine

5 residuesapprox. 545.64 Dacharge +2 / -0 / net +2basic 2 • polar 3

Sequence-derived properties

Sequence-derived properties are omitted because the stored sequence includes non-residue terminal modifiers.

Sources

  1. 48Palmitoyl Pentapeptide-4 - R&D PEPTIDE.ONE, https://rnd.peptide.one/product/palmitoyl-pentapeptide-4-pal-lys-thr-thr-lys-ser/
  2. 51[PDF] Acetyl tetrapeptide-5 - SkinMiles, https://skinmiles.com/wp-content/uploads/2017/12/Matriskin-Ingredients.pdf
  3. 58[PDF] Safety Assessment of Myristoyl Pentapeptide-4, Palmitoyl ..., https://www.cir-safety.org/sites/default/files/Pentapeptide%20Ingredients.pdf

Related articles

No related articles are linked to this peptide yet.