Comparison
While Dulaglutide is a once-weekly GLP-1RA for type 2 diabetes that lowers HbA1c and body weight by enhancing glucose-dependent insulin secretion and reducing appetite6668, Selank is a peptide developed in Russia as an anxiolytic and nootropic; in animal models it reduces anxiety-like behavior and modulates immune parameters under stress39.
While Dulaglutide works as a recombinant fusion protein consisting of two disulfide-linked GLP-1(7–37) analogs each covalently fused via a linker to an IgG4 Fc fragment, yielding a large, long-acting GLP-1 receptor agonist protected from DPP-4 degradation66, Selank is a synthetic heptapeptide, Thr-Lys-Pro-Arg-Pro-Gly-Pro, that combines a tuftsin fragment with a Pro-Gly-Pro motif and is reported to modulate GABAergic neurotransmission and cytokine balance while being resistant to proteolytic degradation39.
Dulaglutide is amino acids long, whereas Selank is longer as it has a length of 7 amino acids. Dulaglutide is made up of a sequence of sequence data not available in the current dataset. Selank is made up of a sequence of Threonine, Lysine, Proline, Arginine, Proline, Glycine, Proline.
Dulaglutide
GCG
Selank
Not assigned in the current dataset.