Acetyl tetrapeptide-5
is used in cosmetic eye formulations to decrease puffiness, eye bags, and dark circles by reducing edema and protecting proteins such as SOD from glycation
Alanine
Ala / A · hydrophobic residue · neutral charge
AOD-9604
is studied as an anti-obesity peptide that can reduce weight gain and increase fat oxidation in obese animal models with generally neutral effects on IGF-1 and glucose metabolism in early human trials
Arginine
Arg / R · basic residue · positive charge
Argireline
is a topical cosmetic peptide reported to decrease dynamic wrinkles by partially mimicking the mechanism of botulinum toxin in a non-invasive manner
Asparagine
Asn / N · polar residue · neutral charge
Aspartic acid
Asp / D · acidic residue · negative charge
BPC-157
is investigated for accelerating healing of gastrointestinal mucosa, tendons, ligaments, bone, and nervous tissue in preclinical models, with anti-inflammatory and pro-angiogenic effects
Comparison
While BPC-157 is investigated for accelerating healing of gastrointestinal mucosa, tendons, ligaments, bone, and nervous tissue in preclinical models, with anti-inflammatory and pro-angiogenic effects111, LL-37 acts as a broad-spectrum antimicrobial and immunomodulatory peptide involved in host defense and wound repair, but can also promote inflammation and cancer cell proliferation in some contexts5215.
While BPC-157 works as a synthetic 15-amino-acid fragment of a gastric cytoprotective protein that promotes angiogenesis and tissue protection primarily by modulating VEGFR2 signaling, Src/caveolin-1–dependent eNOS activation, and nitric oxide production111, LL-37 is a cationic amphipathic 37-amino-acid cathelicidin peptide generated from hCAP18 that disrupts microbial membranes and modulates innate immunity, including chemotaxis, cytokine induction, and NET formation521586.
BPC-157
Not assigned in the current dataset.
LL-37
CAMP
The clearest overlap between BPC-157 and LL-37 is that both converge around Signaling modulator. Both are often discussed in Gastroenterology contexts, while BPC-157 is more of a signal peptide and LL-37 is better described as a antimicrobial peptide and Immune-modulating peptide. Both appear to work through Signaling modulator, but the functional emphasis still separates, with BPC-157 leaning toward Angiogenesis modulation and Anti-inflammatory and LL-37 leaning toward Anti-pathogenic and Immune regulation. BPC-157 has a more synthetic analog origin, while LL-37 is closer to natural endogenous background and both are still best understood as being in Preclinical development. Their sequence patterns also diverge, with BPC-157 showing proline-rich features and LL-37 showing cationic amphipathic and alpha-helical domain features.