Acetyl tetrapeptide-5
is used in cosmetic eye formulations to decrease puffiness, eye bags, and dark circles by reducing edema and protecting proteins such as SOD from glycation
Alanine
Ala / A · hydrophobic residue · neutral charge
AOD-9604
is studied as an anti-obesity peptide that can reduce weight gain and increase fat oxidation in obese animal models with generally neutral effects on IGF-1 and glucose metabolism in early human trials
Arginine
Arg / R · basic residue · positive charge
Argireline
is a topical cosmetic peptide reported to decrease dynamic wrinkles by partially mimicking the mechanism of botulinum toxin in a non-invasive manner
Asparagine
Asn / N · polar residue · neutral charge
Aspartic acid
Asp / D · acidic residue · negative charge
BPC-157
is investigated for accelerating healing of gastrointestinal mucosa, tendons, ligaments, bone, and nervous tissue in preclinical models, with anti-inflammatory and pro-angiogenic effects
Peptide record
Peptide record
LL-37 is a Antimicrobial peptide.
This Peptide acts as a broad-spectrum antimicrobial and immunomodulatory peptide involved in host defense and wound repair, but can also promote inflammation and cancer cell proliferation in some contexts5215
LL-37 is a cationic amphipathic 37-amino-acid cathelicidin peptide generated from hCAP18 that disrupts microbial membranes and modulates innate immunity, including chemotaxis, cytokine induction, and NET formation521586
LL-37 is a Membrane disruptor.
Functions as a ligand for CXCR2 on neutrophils and other myeloid cells; LL-37 signaling has also been linked to FPR2 and P2X7 in various cell types515
37 amino acids
Human cathelicidin antimicrobial peptide generated from the CAP-18 precursor5286
CAMP
LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES 86
Leucine, Leucine, Glycine, Aspartic acid, Phenylalanine, Phenylalanine, Arginine, Lysine, Serine, Lysine, Glutamic acid, Lysine, Isoleucine, Glycine, Lysine, Glutamic acid, Phenylalanine, Lysine, Arginine, Isoleucine, Valine, Glutamine, Arginine, Isoleucine, Lysine, Aspartic acid, Phenylalanine, Leucine, Arginine, Asparagine, Leucine, Valine, Proline, Arginine, Threonine, Glutamic acid, Serine
Length
37 residues
Molecular weight
4493.34 Da
Average hydrophobicity
-0.72
Unique amino acids
14
hydrophobic
13 (35.1%)
basic
11 (29.7%)
acidic
5 (13.5%)
polar
5 (13.5%)
special
3 (8.1%)
neutral
21 (56.8%)
positive
11 (29.7%)
negative
5 (13.5%)
Lysine (Lys/K)
6 (16.2%)
Arginine (Arg/R)
5 (13.5%)
Leucine (Leu/L)
4 (10.8%)
Phenylalanine (Phe/F)
4 (10.8%)
Glutamic acid (Glu/E)
3 (8.1%)
Isoleucine (Ile/I)
3 (8.1%)
Aspartic acid (Asp/D)
2 (5.4%)
Glycine (Gly/G)
2 (5.4%)
Serine (Ser/S)
2 (5.4%)
Valine (Val/V)
2 (5.4%)
Asparagine (Asn/N)
1 (2.7%)
Glutamine (Gln/Q)
1 (2.7%)
Proline (Pro/P)
1 (2.7%)
Threonine (Thr/T)
1 (2.7%)
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