Comparison
While Argireline is a topical cosmetic peptide reported to decrease dynamic wrinkles by partially mimicking the mechanism of botulinum toxin in a non-invasive manner49, Epitalon is reported to increase lifespan and reduce tumor incidence in animals, and to influence differentiation of neural and mesenchymal stem cells; is studied as an epigenetic regulatory peptide36.
While Argireline works as acetyl hexapeptide-8 (Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2), a SNAP-25–mimetic peptide that competitively inhibits SNARE complex assembly, reducing acetylcholine release at neuromuscular junctions and attenuating facial muscle contraction4959, Epitalon is a synthetic tetrapeptide, Ala-Glu-Asp-Gly (AEDG), that has been shown to bind histones and modulate gene expression and chromatin state, with reported effects on pineal function, neurogenesis, and longevity in animal models36.
Argireline is 6 amino acids long, whereas Epitalon is shorter as it has a length of 4 amino acids. Argireline is made up of a sequence of Glutamic acid, Glutamic acid, Methionine, Glutamine, Arginine, Arginine. Epitalon is made up of a sequence of Alanine, Glutamic acid, Aspartic acid, Glycine.
Argireline
Not assigned in the current dataset.
Epitalon
Not assigned in the current dataset.
No related articles are linked to these peptides yet.