Comparison
While Acetyl tetrapeptide-5 is used in cosmetic eye formulations to decrease puffiness, eye bags, and dark circles by reducing edema and protecting proteins such as SOD from glycation51150159154, PEG-MGF is used experimentally to enhance muscle repair and hypertrophy after mechanical overload or injury by stimulating satellite-cell activation and protein synthesis6373138.
While Acetyl tetrapeptide-5 works as a synthetic tetrapeptide, Ac-βAla-His-Ser-His (Eyeseryl), with reported ACE-1 inhibition and anti-glycation activity, proposed to improve microcirculation and reduce capillary permeability and fluid accumulation in periorbital tissues51150159157, PEG-MGF is a poly(ethylene glycol)-conjugated form of Mechano Growth Factor (IGF-1Ec splice variant) comprising the 24-aa C-terminal E-peptide of IGF-1, designed to extend half-life while activating IGF-1 receptor–mediated anabolic signaling in muscle satellite cells637322138.
Acetyl tetrapeptide-5 is 4 amino acids long, whereas PEG-MGF is longer as it has a length of 24 amino acids. Acetyl tetrapeptide-5 is made up of a sequence of βAla, Histidine, Serine, Histidine. PEG-MGF is made up of a sequence of Tyrosine, Glutamine, Proline, Proline, Serine, Threonine, Asparagine, Lysine, Asparagine, Threonine, Lysine, Serine, Glutamine, Arginine, Arginine, Lysine, Glycine, Serine, Threonine, Phenylalanine, Glutamic acid, Glutamic acid, Arginine, Lysine.
Acetyl tetrapeptide-5
Not assigned in the current dataset.
PEG-MGF
IGF1
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