Function
Snap-8 is a Neuropeptide.
This Peptide is a cosmetic peptide studied for reducing wrinkle depth by inhibiting synaptic vesicle fusion and subsequent muscle contraction in facial expression muscles5060
Peptide record
Snap-8
Peptide record
Snap-8
Mechanism
Snap-8 is acetyl octapeptide-3 (Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2), an extended analog of Argireline derived from the N-terminal region of SNAP-25 that competes with native SNAP-25 for binding to syntaxin-1, forming a non-functional SNARE complex and reducing neurotransmitter release5060
Snap-8 is a Neurotransmitter modulator.
Receptor
Targets the SNARE complex (SNAP-25–syntaxin interaction) rather than a cell-surface receptor5060
Length
8 amino acids
Organism or Origin
Fully synthetic SNAP-25–derived peptide used in topical anti-wrinkle products5060
Gene
Not assigned in the current dataset.
Sequence
Ac-EEMQRRAD-NH2 60
Glutamic acid, Glutamic acid, Methionine, Glutamine, Arginine, Arginine, Alanine, Aspartic acid
8 residuesapprox. 1016.11 Dacharge +2 / -3 / net -1acidic 3 • hydrophobic 2 • polar 1 • basic 2
Sequence-derived properties
Sequence-derived properties are omitted because the stored sequence includes non-residue terminal modifiers.
Sources
- 50SNAP-8 (Acetyl Octapeptide-3) Peptide Overview - Kimera Chems, https://kimerachems.co/product/snap-8-acetyl-octapeptide-3/
- 60SNAP-8 (Acetyl Octapeptide-3): The Topical Anti-Wrinkle | FormBlends, https://formblends.com/research/specialty/snap8-anti-aging-peptide
Related articles
No related articles are linked to this peptide yet.