Peptide record

Snap-8

Mechanism

Acetyl octapeptide-3 (Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2), an extended analog of Argireline derived from the N-terminal region of SNAP-25 that competes with native SNAP-25 for binding to syntaxin-1, forming a non-functional SNARE complex and reducing neurotransmitter release.50 60

Function

Cosmetic peptide studied for reducing wrinkle depth by inhibiting synaptic vesicle fusion and subsequent muscle contraction in facial expression muscles.50 60

Receptor

Targets the SNARE complex (SNAP-25–syntaxin interaction) rather than a cell-surface receptor.50 60

Sequence

Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH260

Length

8 amino acids

Organism or Origin

Fully synthetic SNAP-25–derived peptide used in topical anti-wrinkle products.50 60

Gene

Not assigned in the current dataset.

Sources

50SNAP-8 (Acetyl Octapeptide-3) Peptide Overview - Kimera Chems, https://kimerachems.co/product/snap-8-acetyl-octapeptide-3/
60SNAP-8 (Acetyl Octapeptide-3): The Topical Anti-Wrinkle | FormBlends, https://formblends.com/research/specialty/snap8-anti-aging-peptide

No related articles are linked to this peptide yet.