Peptable

Peptide record

Snap-8

Function

Snap-8 is a Neuropeptide.

This Peptide is a cosmetic peptide studied for reducing wrinkle depth by inhibiting synaptic vesicle fusion and subsequent muscle contraction in facial expression muscles5060

Mechanism

Snap-8 is acetyl octapeptide-3 (Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2), an extended analog of Argireline derived from the N-terminal region of SNAP-25 that competes with native SNAP-25 for binding to syntaxin-1, forming a non-functional SNARE complex and reducing neurotransmitter release5060

Snap-8 is a Neurotransmitter modulator.

Receptor

Targets the SNARE complex (SNAP-25–syntaxin interaction) rather than a cell-surface receptor5060

Length

8 amino acids

Organism or Origin

Fully synthetic SNAP-25–derived peptide used in topical anti-wrinkle products5060

Gene

Not assigned in the current dataset.

Sequence

AcN-terminusC-terminusNH2

Ac-EEMQRRAD-NH2 60

Glutamic acid, Glutamic acid, Methionine, Glutamine, Arginine, Arginine, Alanine, Aspartic acid

8 residuesapprox. 1016.11 Dacharge +2 / -3 / net -1acidic 3 • hydrophobic 2 • polar 1 • basic 2

Sequence-derived properties

Sequence-derived properties are omitted because the stored sequence includes non-residue terminal modifiers.

Sources

  1. 50SNAP-8 (Acetyl Octapeptide-3) Peptide Overview - Kimera Chems, https://kimerachems.co/product/snap-8-acetyl-octapeptide-3/
  2. 60SNAP-8 (Acetyl Octapeptide-3): The Topical Anti-Wrinkle | FormBlends, https://formblends.com/research/specialty/snap8-anti-aging-peptide

Related articles

No related articles are linked to this peptide yet.

About this page

Published by
Peptable, as a structured reference dataset.
Dataset updated
Sourcing
Compiled from published literature and reference databases. See the editorial policy.

This page is reference information, not medical advice, and describes no dosages or administration protocols. Read the full disclaimer.