Mechanism
Synthetic 29-amino-acid peptide identical to the 1–29 N-terminal fragment of human GHRH that stimulates GH synthesis and secretion by binding pituitary GHRH receptors.1727120
Peptide record
Sermorelin
Function
Used as a diagnostic agent for assessing GH secretory capacity and as a research tool or off-label therapy to increase endogenous GH in GH-deficient or age-related contexts.1727
Receptor
Growth hormone–releasing hormone receptor (GHRHR) on pituitary somatotrophs.94103120
Sequence
Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2 (YADAIFTNSYRKVLGQLSARKLLQDIMSR)27
Length
29 amino acids
Organism or Origin
Synthetic peptide corresponding to human hypothalamic GHRH(1–29). 17120
Gene
GHRH
Sources
- 17Sermorelin - Wikipedia, https://en.wikipedia.org/wiki/Sermorelin
- 27Sermorelin, https://pubchem.ncbi.nlm.nih.gov/compound/Sermorelin
- 94Growth-hormone-releasing hormone receptor - Wikipedia, https://en.wikipedia.org/wiki/Growth-hormone-releasing_hormone_receptor
- 103Growth-hormone-releasing hormone receptor - Wikipedia, https://en.wikipedia.org/wiki/Growth_hormone_releasing_hormone_receptor
- 120Growth hormone–releasing hormone - Wikipedia, https://en.wikipedia.org/wiki/Growth_hormone%E2%80%93releasing_hormone
Related articles
No related articles are linked to this peptide yet.