Peptable

Acetyl tetrapeptide-5

is used in cosmetic eye formulations to decrease puffiness, eye bags, and dark circles by reducing edema and protecting proteins such as SOD from glycation

Peptide

Alanine

Ala / A · hydrophobic residue · neutral charge

Amino acid

AOD-9604

is studied as an anti-obesity peptide that can reduce weight gain and increase fat oxidation in obese animal models with generally neutral effects on IGF-1 and glucose metabolism in early human trials

Peptide

Arginine

Arg / R · basic residue · positive charge

Amino acid

Argireline

is a topical cosmetic peptide reported to decrease dynamic wrinkles by partially mimicking the mechanism of botulinum toxin in a non-invasive manner

Peptide

Asparagine

Asn / N · polar residue · neutral charge

Amino acid

Aspartic acid

Asp / D · acidic residue · negative charge

Amino acid

BPC-157

is investigated for accelerating healing of gastrointestinal mucosa, tendons, ligaments, bone, and nervous tissue in preclinical models, with anti-inflammatory and pro-angiogenic effects

Peptide

Peptide record

Sermorelin

Function

Sermorelin is a Hormone peptide.

This Peptide is used as a diagnostic agent for assessing GH secretory capacity and as a research tool or off-label therapy to increase endogenous GH in GH-deficient or age-related contexts1727

Mechanism

Sermorelin is a synthetic 29-amino-acid peptide identical to the 1–29 N-terminal fragment of human GHRH that stimulates GH synthesis and secretion by binding pituitary GHRH receptors1727120

Sermorelin is a Receptor agonist.

Receptor

Growth hormone–releasing hormone receptor (GHRHR) on pituitary somatotrophs94103120

Length

29 amino acids

Organism or Origin

Synthetic peptide corresponding to human hypothalamic GHRH(1–29) 17120

Gene

GHRH

Sequence

N-terminus
Tyr
Ala
Asp
Ala
Ile
Phe
Thr
Asn
Ser
Tyr
Arg
Lys
Val
Leu
Gly
Gln
Leu
Ser
Ala
Arg
Lys
Leu
Leu
Gln
Asp
Ile
Met
Ser
Arg
C-terminusNH2

YADAIFTNSYRKVLGQLSARKLLQDIMSR-NH2 27

Tyrosine, Alanine, Aspartic acid, Alanine, Isoleucine, Phenylalanine, Threonine, Asparagine, Serine, Tyrosine, Arginine, Lysine, Valine, Leucine, Glycine, Glutamine, Leucine, Serine, Alanine, Arginine, Lysine, Leucine, Leucine, Glutamine, Aspartic acid, Isoleucine, Methionine, Serine, Arginine

29 residuesapprox. 3340.91 Dacharge +5 / -2 / net +3polar 9 • hydrophobic 12 • acidic 2 • basic 5 • special 1

Sequence-derived properties

Sequence-derived properties are omitted because the stored sequence includes non-residue terminal modifiers.

Sources

  1. 17Sermorelin - Wikipedia, https://en.wikipedia.org/wiki/Sermorelin
  2. 27Sermorelin, https://pubchem.ncbi.nlm.nih.gov/compound/Sermorelin
  3. 94Growth-hormone-releasing hormone receptor - Wikipedia, https://en.wikipedia.org/wiki/Growth-hormone-releasing_hormone_receptor
  4. 103Growth-hormone-releasing hormone receptor - Wikipedia, https://en.wikipedia.org/wiki/Growth_hormone_releasing_hormone_receptor
  5. 120Growth hormone–releasing hormone - Wikipedia, https://en.wikipedia.org/wiki/Growth_hormone%E2%80%93releasing_hormone

Related articles

No related articles are linked to this peptide yet.