Acetyl tetrapeptide-5
is used in cosmetic eye formulations to decrease puffiness, eye bags, and dark circles by reducing edema and protecting proteins such as SOD from glycation
Alanine
Ala / A · hydrophobic residue · neutral charge
AOD-9604
is studied as an anti-obesity peptide that can reduce weight gain and increase fat oxidation in obese animal models with generally neutral effects on IGF-1 and glucose metabolism in early human trials
Arginine
Arg / R · basic residue · positive charge
Argireline
is a topical cosmetic peptide reported to decrease dynamic wrinkles by partially mimicking the mechanism of botulinum toxin in a non-invasive manner
Asparagine
Asn / N · polar residue · neutral charge
Aspartic acid
Asp / D · acidic residue · negative charge
BPC-157
is investigated for accelerating healing of gastrointestinal mucosa, tendons, ligaments, bone, and nervous tissue in preclinical models, with anti-inflammatory and pro-angiogenic effects
Peptide record
Peptide record
Semax is a Neuropeptide.
This Peptide is used clinically in Russia for ischemic stroke and cognitive disorders; in models it improves learning, protects dopaminergic neurons, and modulates stress responses without significant endocrine ACTH-like effects166174
Semax is a synthetic heptapeptide, Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP), that is an analog of ACTH(4–10) with a Pro-Gly-Pro extension and exerts neurotrophic and neuroprotective actions partly via upregulation of BDNF and modulation of dopaminergic and glutamatergic systems40162165174
Semax is a Neurotransmitter modulator.
Targets are not fully defined; interacts with melanocortin-related pathways and inhibits certain peptidases, but no single dominant receptor has been established174
7 amino acids
Synthetic analog of human ACTH(4–10) derived from POMC1748190
POMC
Methionine, Glutamic acid, Histidine, Phenylalanine, Proline, Glycine, Proline
Length
7 residues
Molecular weight
813.94 Da
Average hydrophobicity
-0.8
Unique amino acids
6
special
3 (42.9%)
hydrophobic
2 (28.6%)
acidic
1 (14.3%)
basic
1 (14.3%)
neutral
5 (71.4%)
negative
1 (14.3%)
positive
1 (14.3%)
Proline (Pro/P)
2 (28.6%)
Glutamic acid (Glu/E)
1 (14.3%)
Glycine (Gly/G)
1 (14.3%)
Histidine (His/H)
1 (14.3%)
Methionine (Met/M)
1 (14.3%)
Phenylalanine (Phe/F)
1 (14.3%)
No related articles are linked to this peptide yet.
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