Peptide record

Melanotan II

Mechanism

Cyclic heptapeptide melanocortin analog (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2) that acts as a non-selective, high-potency agonist at MC1R, MC3R, MC4R, and MC5R, influencing pigmentation, appetite, and sexual behavior.35 45

Function

Studied as a tanning and libido-enhancing agent; increases melanin production and can reduce food intake and modulate sexual arousal in animal models and humans.35 45

Receptor

Melanocortin receptors MC1R, MC3R, MC4R, and MC5R (non-selective agonist). 35 45

Sequence

Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH245

Length

7 amino acids

Organism or Origin

Synthetic analog of POMC-derived melanocortin peptides.35 81 90

Gene

POMC

Sources

35What is melanotan II? - Creative Peptides, https://www.creative-peptides.com/resources/what-is-melanotan-ii-peptide.html
45[PDF] melanotan-II peptide structure and molecular formula - Benchchem, https://www.benchchem.com/pdf/melanotan_II_peptide_structure_and_molecular_formula.pdf
81Proopiomelanocortin (POMC), the ACTH/melanocortin precursor, is ..., https://pmc.ncbi.nlm.nih.gov/articles/PMC2253185/
90alpha-Melanocyte stimulating hormone: production and degradation, https://pmc.ncbi.nlm.nih.gov/articles/PMC3936413/

No related articles are linked to this peptide yet.