Peptable

Peptide record

Liraglutide

Function

Liraglutide is a Metabolic peptide.

This Peptide is approved for type 2 diabetes and weight management, improving glycemic control and inducing weight loss through GLP-1–mediated insulinotropic, glucagonostatic, and appetite-suppressing actions6880

Mechanism

Liraglutide is a human GLP-1 analog with a single amino-acid substitution (Lys34→Arg) and a C16 palmitoyl fatty acid attached to Lys26 via a glutamate linker, producing a long-acting GLP-1 receptor agonist6880

Liraglutide is a Receptor agonist.

Receptor

GLP-1 receptor (GLP1R) 6880

Sequence note

GLP-1(7–37) analog with 97% sequence homology to native GLP-1, incorporating Lys34Arg and a C16 acyl chain on Lys26; 31 amino acids 68

Length

31 amino acids

Organism or Origin

Synthetic analog of human GLP-16880

Gene

GCG

Sequence-derived properties

Sequence data is not available in the current dataset.

Sources

  1. 68Glucagon-like peptide-1 analogues: An overview - PMC, https://pmc.ncbi.nlm.nih.gov/articles/PMC3712370/
  2. 80GLP-1 Localisation and Proglucagon Gene Expression in ..., https://pmc.ncbi.nlm.nih.gov/articles/PMC6200298/

Related articles

About this page

Published by
Peptable, as a structured reference dataset.
Dataset updated
Sourcing
Compiled from published literature and reference databases. See the editorial policy.

This page is reference information, not medical advice, and describes no dosages or administration protocols. Read the full disclaimer.