Peptable

Peptide record

GHRP-6

Function

GHRP-6 is a Hormone peptide.

This Peptide is used experimentally to produce strong GH surges and hyperphagia, allowing investigation of GH-dependent anabolism and energy-balance regulation2030

Mechanism

GHRP-6 is a first-generation synthetic hexapeptide ghrelin mimetic that potently stimulates GH release and markedly increases appetite via GHSR-1a activation in hypothalamus and pituitary203096

GHRP-6 is a Receptor agonist.

Receptor

Ghrelin/growth hormone secretagogue receptor (GHSR-1a) 203096104

Length

6 amino acids

Organism or Origin

Synthetic peptide analog of met-enkephalin30

Gene

GHSR

Sequence

N-terminusC-terminusNH2

H-D-W-A-W-D-F-K-NH2 2030

Histidine, Tryptophan, Alanine, Tryptophan, Phenylalanine, Lysine

6 residuesapprox. 855.99 Dacharge +2 / -0 / net +2basic 2 • hydrophobic 4

Sequence-derived properties

Sequence-derived properties are omitted because the stored sequence includes non-residue terminal modifiers.

Sources

  1. 20GHRP-6: The Original GHRP Research Overview - Peptidings, https://peptidings.com/peptides/ghrp-6/
  2. 30GHRP-6 - Wikipedia, https://en.wikipedia.org/wiki/GHRP-6
  3. 96Growth Hormone Secretagogue Receptor - ScienceDirect.com, https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/growth-hormone-secretagogue-receptor
  4. 104Variations in the Ghrelin Receptor Gene Associate with Obesity and Glucose Metabolism in Individuals with Impaired Glucose Tolerance, https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0002941

Related articles

No related articles are linked to this peptide yet.

About this page

Published by
Peptable, as a structured reference dataset.
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Compiled from published literature and reference databases. See the editorial policy.

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