Peptide record

GHRP-6

Mechanism

First-generation synthetic hexapeptide ghrelin mimetic that potently stimulates GH release and markedly increases appetite via GHSR-1a activation in hypothalamus and pituitary.20 30 96

Function

Used experimentally to produce strong GH surges and hyperphagia, allowing investigation of GH-dependent anabolism and energy-balance regulation.20 30

Receptor

Ghrelin/growth hormone secretagogue receptor (GHSR-1a). 20 30 96 104

Sequence

His-D-Trp-Ala-Trp-D-Phe-Lys-NH220 30

Length

6 amino acids

Organism or Origin

Synthetic peptide analog of met-enkephalin.30

Gene

GHSR

Sources

20GHRP-6: The Original GHRP Research Overview - Peptidings, https://peptidings.com/peptides/ghrp-6/
30GHRP-6 - Wikipedia, https://en.wikipedia.org/wiki/GHRP-6
96Growth Hormone Secretagogue Receptor - ScienceDirect.com, https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/growth-hormone-secretagogue-receptor
104Variations in the Ghrelin Receptor Gene Associate with Obesity and Glucose Metabolism in Individuals with Impaired Glucose Tolerance, https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0002941

No related articles are linked to this peptide yet.