Acetyl tetrapeptide-5

is used in cosmetic eye formulations to decrease puffiness, eye bags, and dark circles by reducing edema and protecting proteins such as SOD from glycation

Alanine

Ala / A · hydrophobic residue · neutral charge

AOD-9604

is studied as an anti-obesity peptide that can reduce weight gain and increase fat oxidation in obese animal models with generally neutral effects on IGF-1 and glucose metabolism in early human trials

Arginine

Arg / R · basic residue · positive charge

Argireline

is a topical cosmetic peptide reported to decrease dynamic wrinkles by partially mimicking the mechanism of botulinum toxin in a non-invasive manner

Asparagine

Asn / N · polar residue · neutral charge

Aspartic acid

Asp / D · acidic residue · negative charge

BPC-157

is investigated for accelerating healing of gastrointestinal mucosa, tendons, ligaments, bone, and nervous tissue in preclinical models, with anti-inflammatory and pro-angiogenic effects

Peptide record

GHRP-6

Peptide record

GHRP-6

Function

GHRP-6 is a Hormone peptide.

This Peptide is used experimentally to produce strong GH surges and hyperphagia, allowing investigation of GH-dependent anabolism and energy-balance regulation20 30

Mechanism

GHRP-6 is a first-generation synthetic hexapeptide ghrelin mimetic that potently stimulates GH release and markedly increases appetite via GHSR-1a activation in hypothalamus and pituitary20 30 96

GHRP-6 is a Receptor agonist.

Receptor

Ghrelin/growth hormone secretagogue receptor (GHSR-1a) 20 30 96 104

Length

6 amino acids

Organism or Origin

Synthetic peptide analog of met-enkephalin30

Gene

GHSR

Sequence

N-terminus

C-terminusNH2

H-D-W-A-W-D-F-K-NH2 20 30

Histidine, Tryptophan, Alanine, Tryptophan, Phenylalanine, Lysine

6 residuesapprox. 855.99 Dacharge +2 / -0 / net +2basic 2 • hydrophobic 4

Sequence-derived properties

Sequence-derived properties are omitted because the stored sequence includes non-residue terminal modifiers.

Sources

20GHRP-6: The Original GHRP Research Overview - Peptidings, https://peptidings.com/peptides/ghrp-6/
30GHRP-6 - Wikipedia, https://en.wikipedia.org/wiki/GHRP-6
96Growth Hormone Secretagogue Receptor - ScienceDirect.com, https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/growth-hormone-secretagogue-receptor
104Variations in the Ghrelin Receptor Gene Associate with Obesity and Glucose Metabolism in Individuals with Impaired Glucose Tolerance, https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0002941

Related articles

No related articles are linked to this peptide yet.