Peptable

Peptide record

GHRP-2

Function

GHRP-2 is a Hormone peptide.

This Peptide is used in research to induce robust GH pulses and study anabolic and metabolic effects; clinically developed as pralmorelin for GH deficiency diagnostics6272

Mechanism

GHRP-2 is a second-generation hexapeptide growth hormone–releasing peptide that mimics ghrelin by agonizing GHSR-1a, strongly stimulating pulsatile GH release and modestly raising prolactin, ACTH, and cortisol62723096

GHRP-2 is a Receptor agonist.

Receptor

Ghrelin/growth hormone secretagogue receptor (GHSR-1a) 309596104

Length

6 amino acids

Organism or Origin

Synthetic met-enkephalin–derived hexapeptide3072

Gene

GHSR

Sequence

N-terminusC-terminusNH2

D-A-D-2-Nal-A-W-D-F-K-NH2 6272

Alanine, D-2-Nal, Alanine, Tryptophan, Phenylalanine, Lysine

6 residuesapprox. 603.72 Dacharge +1 / -0 / net +1hydrophobic 4 • basic 11 residues without standard metadata

Sequence-derived properties

Sequence-derived properties are omitted because the stored sequence includes non-residue terminal modifiers.

Sequence-derived properties are omitted because one or more residues are not present in the standard amino-acid dataset.

Sources

  1. 30GHRP-6 - Wikipedia, https://en.wikipedia.org/wiki/GHRP-6
  2. 62GHRP-2: Potent Growth Hormone Releasing Peptide Guide, https://www.peptidepedia.org/performance/ghrp-2
  3. 72GHRP-2 Technical Data - Molecular Specs - Peptide Initiative, https://peptideinitiative.com/peptides/ghrp-2/technical
  4. 95Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren, https://www.nature.com/articles/s41467-021-26735-5
  5. 96Growth Hormone Secretagogue Receptor - ScienceDirect.com, https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/growth-hormone-secretagogue-receptor
  6. 104Variations in the Ghrelin Receptor Gene Associate with Obesity and Glucose Metabolism in Individuals with Impaired Glucose Tolerance, https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0002941

Related articles

No related articles are linked to this peptide yet.

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Published by
Peptable, as a structured reference dataset.
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Compiled from published literature and reference databases. See the editorial policy.

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