Acetyl tetrapeptide-5

is used in cosmetic eye formulations to decrease puffiness, eye bags, and dark circles by reducing edema and protecting proteins such as SOD from glycation

Alanine

Ala / A · hydrophobic residue · neutral charge

AOD-9604

is studied as an anti-obesity peptide that can reduce weight gain and increase fat oxidation in obese animal models with generally neutral effects on IGF-1 and glucose metabolism in early human trials

Arginine

Arg / R · basic residue · positive charge

Argireline

is a topical cosmetic peptide reported to decrease dynamic wrinkles by partially mimicking the mechanism of botulinum toxin in a non-invasive manner

Asparagine

Asn / N · polar residue · neutral charge

Aspartic acid

Asp / D · acidic residue · negative charge

BPC-157

is investigated for accelerating healing of gastrointestinal mucosa, tendons, ligaments, bone, and nervous tissue in preclinical models, with anti-inflammatory and pro-angiogenic effects

Peptide record

GHRP-2

Peptide record

GHRP-2

Function

GHRP-2 is a Hormone peptide.

This Peptide is used in research to induce robust GH pulses and study anabolic and metabolic effects; clinically developed as pralmorelin for GH deficiency diagnostics62 72

Mechanism

GHRP-2 is a second-generation hexapeptide growth hormone–releasing peptide that mimics ghrelin by agonizing GHSR-1a, strongly stimulating pulsatile GH release and modestly raising prolactin, ACTH, and cortisol62 72 30 96

GHRP-2 is a Receptor agonist.

Receptor

Ghrelin/growth hormone secretagogue receptor (GHSR-1a) 30 95 96 104

Length

6 amino acids

Organism or Origin

Synthetic met-enkephalin–derived hexapeptide30 72

Gene

GHSR

Sequence

N-terminus

C-terminusNH2

D-A-D-2-Nal-A-W-D-F-K-NH2 62 72

Alanine, D-2-Nal, Alanine, Tryptophan, Phenylalanine, Lysine

6 residuesapprox. 603.72 Dacharge +1 / -0 / net +1hydrophobic 4 • basic 11 residues without standard metadata

Sequence-derived properties

Sequence-derived properties are omitted because the stored sequence includes non-residue terminal modifiers.

Sequence-derived properties are omitted because one or more residues are not present in the standard amino-acid dataset.

Sources

30GHRP-6 - Wikipedia, https://en.wikipedia.org/wiki/GHRP-6
62GHRP-2: Potent Growth Hormone Releasing Peptide Guide, https://www.peptidepedia.org/performance/ghrp-2
72GHRP-2 Technical Data - Molecular Specs - Peptide Initiative, https://peptideinitiative.com/peptides/ghrp-2/technical
95Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren, https://www.nature.com/articles/s41467-021-26735-5
96Growth Hormone Secretagogue Receptor - ScienceDirect.com, https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/growth-hormone-secretagogue-receptor
104Variations in the Ghrelin Receptor Gene Associate with Obesity and Glucose Metabolism in Individuals with Impaired Glucose Tolerance, https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0002941

Related articles

No related articles are linked to this peptide yet.