Function
GHK-Cu is a Signal peptide.
This Peptide acts as a tissue-remodeling and wound-healing signal, enhancing skin regeneration, angiogenesis, and repair while reducing inflammation and oxidative damage in experimental models31383
Peptide record
GHK-Cu
Peptide record
GHK-Cu
Mechanism
GHK-Cu is an endogenous tripeptide, Gly-His-Lys, that chelates Cu²⁺ and modulates gene expression, stimulating collagen, elastin, proteoglycan, and glycosaminoglycan synthesis while exerting antioxidant and anti-inflammatory effects31383
GHK-Cu is a Gene expression modulator.
Receptor
Not clearly established in the current dataset.
Length
3 amino acids
Organism or Origin
Naturally occurring human plasma peptide also found in saliva and urine313
Gene
Not assigned in the current dataset.
Sequence
GHK 83
3 residuesapprox. 322.36 Dacharge +2 / -0 / net +2special 1 • basic 2
Sequence-derived properties
Length
3 residues
Molecular weight
340.38 Da
Average hydrophobicity
-2.5
Unique amino acids
3
Residue class composition
basic
2 (66.7%)
special
1 (33.3%)
Charge-category composition
positive
2 (66.7%)
neutral
1 (33.3%)
Amino acid composition
Glycine (Gly/G)
1 (33.3%)
Histidine (His/H)
1 (33.3%)
Lysine (Lys/K)
1 (33.3%)
Sources
- 3GHK-Cu: Structure And Mechanism Of Action, https://sportstechnologylabs.com/ghk-cu-structure-and-mechanism-of-action/
- 13What is GHK-Cu and How Does it Work?, https://www.peptidesciences.com/peptide-research/what-is-ghk-cu-and-how
- 83What is GHK-Cu | Peptides for sale, https://polarispeptides.com/what-is-ghk-cu/