Peptable

Acetyl tetrapeptide-5

is used in cosmetic eye formulations to decrease puffiness, eye bags, and dark circles by reducing edema and protecting proteins such as SOD from glycation

Peptide

Alanine

Ala / A · hydrophobic residue · neutral charge

Amino acid

AOD-9604

is studied as an anti-obesity peptide that can reduce weight gain and increase fat oxidation in obese animal models with generally neutral effects on IGF-1 and glucose metabolism in early human trials

Peptide

Arginine

Arg / R · basic residue · positive charge

Amino acid

Argireline

is a topical cosmetic peptide reported to decrease dynamic wrinkles by partially mimicking the mechanism of botulinum toxin in a non-invasive manner

Peptide

Asparagine

Asn / N · polar residue · neutral charge

Amino acid

Aspartic acid

Asp / D · acidic residue · negative charge

Amino acid

BPC-157

is investigated for accelerating healing of gastrointestinal mucosa, tendons, ligaments, bone, and nervous tissue in preclinical models, with anti-inflammatory and pro-angiogenic effects

Peptide

Peptide record

GHK-Cu

Function

GHK-Cu is a Signal peptide.

This Peptide acts as a tissue-remodeling and wound-healing signal, enhancing skin regeneration, angiogenesis, and repair while reducing inflammation and oxidative damage in experimental models31383

Mechanism

GHK-Cu is an endogenous tripeptide, Gly-His-Lys, that chelates Cu²⁺ and modulates gene expression, stimulating collagen, elastin, proteoglycan, and glycosaminoglycan synthesis while exerting antioxidant and anti-inflammatory effects31383

GHK-Cu is a Gene expression modulator.

Receptor

Not clearly established in the current dataset.

Length

3 amino acids

Organism or Origin

Naturally occurring human plasma peptide also found in saliva and urine313

Gene

Not assigned in the current dataset.

Sequence

N-terminus
Gly
His
Lys
C-terminus

GHK 83

Glycine, Histidine, Lysine

3 residuesapprox. 322.36 Dacharge +2 / -0 / net +2special 1 • basic 2

Sequence-derived properties

Length

3 residues

Molecular weight

340.38 Da

Average hydrophobicity

-2.5

Unique amino acids

3

Residue class composition

basic

2 (66.7%)

special

1 (33.3%)

Charge-category composition

positive

2 (66.7%)

neutral

1 (33.3%)

Amino acid composition

Glycine (Gly/G)

1 (33.3%)

Histidine (His/H)

1 (33.3%)

Lysine (Lys/K)

1 (33.3%)

Sources

  1. 3GHK-Cu: Structure And Mechanism Of Action, https://sportstechnologylabs.com/ghk-cu-structure-and-mechanism-of-action/
  2. 13What is GHK-Cu and How Does it Work?, https://www.peptidesciences.com/peptide-research/what-is-ghk-cu-and-how
  3. 83What is GHK-Cu | Peptides for sale, https://polarispeptides.com/what-is-ghk-cu/

Related articles

GHK-Cu (Glycyl-L-Histidyl-L-Lysine-Copper)

About this page

Published by
Peptable, as a structured reference dataset.
Dataset updated
Sourcing
Compiled from published literature and reference databases. See the editorial policy.

This page is reference information, not medical advice, and describes no dosages or administration protocols. Read the full disclaimer.