Peptable

Acetyl tetrapeptide-5

is used in cosmetic eye formulations to decrease puffiness, eye bags, and dark circles by reducing edema and protecting proteins such as SOD from glycation

Peptide

Alanine

Ala / A · hydrophobic residue · neutral charge

Amino acid

AOD-9604

is studied as an anti-obesity peptide that can reduce weight gain and increase fat oxidation in obese animal models with generally neutral effects on IGF-1 and glucose metabolism in early human trials

Peptide

Arginine

Arg / R · basic residue · positive charge

Amino acid

Argireline

is a topical cosmetic peptide reported to decrease dynamic wrinkles by partially mimicking the mechanism of botulinum toxin in a non-invasive manner

Peptide

Asparagine

Asn / N · polar residue · neutral charge

Amino acid

Aspartic acid

Asp / D · acidic residue · negative charge

Amino acid

BPC-157

is investigated for accelerating healing of gastrointestinal mucosa, tendons, ligaments, bone, and nervous tissue in preclinical models, with anti-inflammatory and pro-angiogenic effects

Peptide

Peptide record

FOXO4-DRI

Function

FOXO4-DRI is a Senolytic peptide.

This Peptide acts as a senolytic in preclinical models by promoting apoptosis of senescent cells, improving tissue function and healthspan measures in aged animals38

Mechanism

FOXO4-DRI is a D-retro-inverso peptide derived from a FOXO4 region that competes with endogenous FOXO4 for binding to p53, thereby releasing p53 to trigger apoptosis selectively in senescent cells38

FOXO4-DRI is a Protein interaction inhibitor.

Receptor

Intracellular target is the FOXO4–p53 protein–protein interaction interface; it does not signal via a traditional cell-surface receptor38

Sequence note

D-retro-inverso version of a FOXO4 peptide segment (exact D-amino-acid sequence defined in the original Erasmus Medical Center work) 38

Length

null amino acids

Organism or Origin

Synthetic peptide based on human FOXO4 transcription factor3898

Gene

FOXO4

Sequence-derived properties

Sequence data is not available in the current dataset.

Sources

  1. 38FOXO4-DRI - Research Information - Peptpedia, https://peptpedia.org/peptide/foxo4-dri
  2. 98Human FOXO4 Synthetic Peptide (PEP-1088), https://www.thermofisher.com/proteins/product/Human-FOXO4-Synthetic-Peptide/PEP-1088

Related articles

No related articles are linked to this peptide yet.

About this page

Published by
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Sourcing
Compiled from published literature and reference databases. See the editorial policy.

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