Peptable

Peptide record

Exenatide

Function

Exenatide is a Metabolic peptide.

This Peptide is used for type 2 diabetes treatment to improve glycemic control and modestly reduce body weight through GLP-1–like insulinotropic and glucagonostatic effects6768

Mechanism

Exenatide is a 39-amino-acid exendin-4 peptide originally isolated from Gila monster venom that acts as a long-acting GLP-1 receptor agonist resistant to DPP-4 degradation67

Exenatide is a Receptor agonist.

Receptor

GLP-1 receptor (GLP1R) 6780

Sequence note

Exendin-4 is a 39-amino-acid peptide incretin mimetic; the full sequence is well characterized but often referenced simply as exendin-4 (39 aa GLP-1R agonist) 67

Length

39 amino acids

Organism or Origin

Originally from Heloderma suspectum (Gila monster) venom; now produced synthetically67

Gene

Not assigned in the current dataset.

Sequence-derived properties

Sequence data is not available in the current dataset.

Sources

  1. 67Exendin 4 – Potent GLP-1R agonist - SB PEPTIDE, https://www.sb-peptide.com/project/exendin-4-potent-glp-1r-agonist/
  2. 68Glucagon-like peptide-1 analogues: An overview - PMC, https://pmc.ncbi.nlm.nih.gov/articles/PMC3712370/
  3. 80GLP-1 Localisation and Proglucagon Gene Expression in ..., https://pmc.ncbi.nlm.nih.gov/articles/PMC6200298/

Related articles

About this page

Published by
Peptable, as a structured reference dataset.
Dataset updated
Sourcing
Compiled from published literature and reference databases. See the editorial policy.

This page is reference information, not medical advice, and describes no dosages or administration protocols. Read the full disclaimer.