Peptable

Peptide record

DSIP

Function

DSIP is a Neuropeptide.

This Peptide was originally described for inducing spindle and delta sleep activity when infused into the brain of rabbits; later studies report stress-modulating and endocrine effects, though its physiological role is still debated47

Mechanism

DSIP is an endogenous nonapeptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, with proposed neuromodulatory actions; it interacts with components of the MAPK cascade and may be related to glucocorticoid-induced leucine zipper (GILZ), but its precise biosynthetic origin remains unknown4757

DSIP is a Neurotransmitter modulator.

Receptor

Not clearly established in the current dataset.

Length

9 amino acids

Organism or Origin

Endogenous vertebrate neuropeptide; its encoding gene has not been identified47

Gene

Not assigned in the current dataset.

Sequence

N-terminusC-terminus

WAGGDASGE 4757

Tryptophan, Alanine, Glycine, Glycine, Aspartic acid, Alanine, Serine, Glycine, Glutamic acid

9 residuesapprox. 830.81 Dacharge +0 / -2 / net -2hydrophobic 3 • special 3 • acidic 2 • polar 1

Sequence-derived properties

Length

9 residues

Molecular weight

848.83 Da

Average hydrophobicity

-0.7

Unique amino acids

6

Residue class composition

hydrophobic

3 (33.3%)

special

3 (33.3%)

acidic

2 (22.2%)

polar

1 (11.1%)

Charge-category composition

neutral

7 (77.8%)

negative

2 (22.2%)

Amino acid composition

Glycine (Gly/G)

3 (33.3%)

Alanine (Ala/A)

2 (22.2%)

Aspartic acid (Asp/D)

1 (11.1%)

Glutamic acid (Glu/E)

1 (11.1%)

Serine (Ser/S)

1 (11.1%)

Tryptophan (Trp/W)

1 (11.1%)

Sources

  1. 47DSIP (Delta sleep-inducing peptide), https://particlepeptides.com/en/content/12-dsip
  2. 57Transport and metabolism of delta sleep-inducing peptide ... - PubMed, https://pubmed.ncbi.nlm.nih.gov/8689946/

Related articles

No related articles are linked to this peptide yet.

About this page

Published by
Peptable, as a structured reference dataset.
Dataset updated
Sourcing
Compiled from published literature and reference databases. See the editorial policy.

This page is reference information, not medical advice, and describes no dosages or administration protocols. Read the full disclaimer.