Peptide record

DSIP

Mechanism

Endogenous nonapeptide Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu with proposed neuromodulatory actions; interacts with components of the MAPK cascade and may be related to glucocorticoid-induced leucine zipper (GILZ), but its precise biosynthetic origin remains unknown.47 57

Function

Originally described for inducing spindle and delta sleep activity when infused into the brain of rabbits; later studies report stress-modulating and endocrine effects, though its physiological role is still debated.47

Receptor

Not clearly established in the current dataset.

Sequence

Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE)47 57

Length

9 amino acids

Organism or Origin

Endogenous vertebrate neuropeptide; its encoding gene has not been identified.47

Gene

Not assigned in the current dataset.

Sources

47DSIP (Delta sleep-inducing peptide), https://particlepeptides.com/en/content/12-dsip
57Transport and metabolism of delta sleep-inducing peptide ... - PubMed, https://pubmed.ncbi.nlm.nih.gov/8689946/

No related articles are linked to this peptide yet.