Comparison
While AOD-9604 is studied as an anti-obesity peptide that can reduce weight gain and increase fat oxidation in obese animal models with generally neutral effects on IGF-1 and glucose metabolism in early human trials71111115, Hexarelin is investigated for effects on GH secretion, cardiac protection, and muscle metabolism, with higher GH secretory potency than earlier GHRPs1929.
While AOD-9604 works as a synthetic fragment of human growth hormone corresponding to residues 176–191 with an added N-terminal tyrosine, retaining lipolytic but not growth-promoting actions; proposed to stimulate lipolysis and inhibit lipogenesis in adipose tissue, partly via β3-adrenergic pathways without significantly activating the full GH receptor–IGF-1 axis6171111, Hexarelin is a potent synthetic hexapeptide (examorelin) that agonizes GHSR-1a to stimulate GH release and also binds CD36, influencing cardiovascular and metabolic pathways19212996.
AOD-9604 is 16 amino acids long, whereas Hexarelin is shorter as it has a length of 6 amino acids. AOD-9604 is made up of a sequence of Tyrosine, Leucine, Arginine, Isoleucine, Valine, Glutamine, Cysteine, Arginine, Serine, Valine, Glutamic acid, Glycine, Serine, Cysteine, Glycine, Phenylalanine. Hexarelin is made up of a sequence of Histidine, Tryptophan, Alanine, Tryptophan, Phenylalanine, Lysine.
AOD-9604
Hexarelin
AOD-9604
GH1
Hexarelin
GHSR
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